Matteo Cremona was born in Como in March 1981. He made his debut with a short story in 2003, in the collection "i Vizi di Pinketts" published by Edizioni BD, then appeared in the book published by Mondadori "Alta Criminalità". Later he joined the staff of designers of the hit series "John Doe", published by Eura Editoriale, for which he drew three issues.
In 2008 he worked together with Roberto Recchioni, who was the writer in the above mentioned series John Doe, in a four issues mini-series "David Murphy 911", published by Panini Comics.
In 2010 he published a short story in a collection of short novels written by Carlo Lucarelli entitled "Il Brigadiere Leonardi", published by Edizioni BD. For the same publisher he has also created an Artbook, made of 12 apocalyptic scenery illustrations, which in 2012 were exhibited in a monographic exhibition.
From 2008 to 2012 he taught at the International School of Comics in Milan.
In 2012 he began his collaborating with Sergio Bonelli Editore, for which he drew the issue #9 of "Le Storie", "Mexican Standoff", written by Diego Cajelli, the issue #10 of the series "Orfani" written by Roberto Recchioni and the issue #9 of the series"Orfani: Ringo" written by Mauro Uzzeo, which was published in June 2015.
In 2014 he presented a twelve episodes TV show called "L'Officina dei Mostri" produced by DeaKids.